Thermo Fisher Scientific NUP153 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NUP153. Recombinant protein control fragment (Product #RP-94811). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NUP153,uniProtId:P49790-1,ncbiNodeId:9606,antigenRange:1024-1132,antigenLength:1475,antigenImageFileName:PA5-55720_NUP153_P49790-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55720_NUP153_P49790-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644892

Product Specific Information

Immunogen sequence: FGTGVINSTP APANTIVTSE NKSSFNLGTI ETKSASVAPF TCKTSEAKKE EMPATKGGFS FGNVEPASLP SASVFVLGRT EEKQQEPVTS TSLVFGKKAD NEEPKCQPV

Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 75%.

Target Information

Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats. Alternative splicing results in multiple transcript variants of this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.