Thermo Fisher Scientific TLR11 Polyclonal Antibody
TLR11 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ELISA, Immunoprecipitation에 사용 가능. 인간 및 영장류 반응성. 고순도 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chimpanzee, Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 430–460 of human TLR11 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Toll-like receptor (TLR) family in mammals comprises transmembrane proteins characterized by multiple leucine-rich repeats in the extracellular domain and an IL-1 receptor motif in the cytoplasmic domain. TLRs signal through adaptor molecules and are key mediators of innate immunity essential for microbial recognition.
TLR11 specifically responds to uropathogenic bacteria rather than known TLR ligands. TLR11-deficient mice are highly susceptible to kidney infection by uropathogenic bacteria, suggesting a protective role in the urogenital system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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