Thermo Fisher Scientific Lyn Monoclonal Antibody (2H8D7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

5 µg/mL

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

2H8D7

Immunogen

Purified recombinant fragment of LYN expressed in E. Coli.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.03% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_10980946

Product Specific Information

MA5-15329 targets LYN in indirect ELISA, WB applications and shows reactivity with Human samples.

The MA5-15329 immunogen is purified recombinant fragment of LYN expressed in E. Coli.

MA5-15329 detects LYN which has a predicted molecular weight of approximately 56kDa.

Target Information

Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well studied expression of Lyn is in hematopoietic cell types, both lymphoid and myeloid cells with exclusion in T lymphocytes. It has also been observed that Lyn plays diverse roles such as in regulation of B cell receptor signaling, mast cell signaling and Epithelial - Mesenchymal Transition (EMT).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.