Thermo Fisher Scientific EEF2K Polyclonal Antibody
EEF2K 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 합성 펩타이드 면역원 기반, 액상형, 1 mg/mL 농도. 단백질 합성 조절 연구용에 적합.
- 카탈로그번호
- PA5102761
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EEF2K (Accession O00418), corresponding to amino acid residues N339–T389 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852152 |
Product Specific Information
Antibody detects endogenous levels of total eEF2K.
Target Information
EEF2K is a highly conserved Serine/Threonine kinase in the calmodulin signaling pathway whose activity is increased in cancers including breast cancer.
EEF2K (eukaryotic elongation factor 2 kinase) regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by upstream kinases such as AMPK or TRPM7, EEF2K phosphorylates elongation factor EEF2 at a single site, rendering EEF2 unable to bind ribosomes and inactive, thus reducing the rate of protein synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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