Thermo Fisher Scientific BCL2L10 Polyclonal Antibody
BCL2L10 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 적용 가능. 인간 및 생쥐 반응성. 고순도 친화 크로마토그래피 정제. 액상 형태, 1 mg/mL 농도, -20°C 보관.
- 카탈로그번호
- PA5100704
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BCL2L10 (Accession Q9HD36), corresponding to amino acid residues G122–Q172 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850208 |
Product Specific Information
Antibody detects endogenous levels of total BCL2L10.
Target Information
The protein encoded by this gene belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in various cellular processes.
This protein contains conserved BH4, BH1, and BH2 domains and interacts with BCL2, BCL2L1/BCL-X(L), and BAX.
Overexpression can suppress apoptosis by preventing cytochrome C release from mitochondria and reducing caspase-3 activation.
In mice, the counterpart interacts with Apaf1 and forms a complex with Caspase 9, indicating involvement in APAF1 and CASPASE 9 related apoptotic pathways.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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