Thermo Fisher Scientific SCAMP2 Monoclonal Antibody (OTI2F1)
SCAMP2 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot, IHC, ICC/IF 등에 사용 가능. 인간 시료 반응성, Mouse IgG1 형, 액상 형태로 제공되며 -20°C에서 보관. 세포막 단백질 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F1 |
| Immunogen | Full length human recombinant protein of SCAMP2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723609 |
Target Information
Secretory carrier membrane proteins (SCAMPs) are components of post-Golgi membranes involved in membrane trafficking.
In fibroblasts, SCAMPs are concentrated in compartments associated with recycling of cell surface receptors and endocytosis.
In neurons, SCAMPs are found in synaptic vesicles, secretion granules, and transporter vesicles.
SCAMPs consist of four central transmembrane regions and a cytoplasmic tail.
Of the five known SCAMPs, SCAMPs 1–3 have N-terminal regions with NPF repeats that interact with EH domain proteins functioning in vesicle budding.
SCAMPs 4 and 5 lack these repeats. SCAMPs 1–4 are ubiquitously expressed, while SCAMP 5 is brain-specific and expressed late in development, coinciding with synapse maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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