Thermo Fisher Scientific LPAP Polyclonal Antibody
Western blot 및 Immunoprecipitation에 적합한 Rabbit Polyclonal Antibody. 인간 LPAP(PTPRCAP) 156-206 영역을 면역원으로 제작. 비결합형 액상 항체로 1 mg/mL 농도 제공. 4°C 보관, Wet ice 배송.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 156 to 206 of human Lymphocyte Phosphatase-Associated Phosphoprotein (PTPRCAP, UniProt ID: Q14761-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
MSK-1 is a mitogen and stress-activated protein kinase-1 belonging to the AGC family of kinases, structurally related to the ribosomal p70 S6 kinase subfamily. It can be activated by ERK1/2 and SAPK2/p38 MAP kinase and is required for phosphorylation of CREB, ATF1, H3, and HMG-14 in response to mitogen and stress. MSK-1 contains two kinase domains (N-terminal and C-terminal). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK-1 autophosphorylates on several sites including Ser212 and Ser376, which are essential for catalytic activity of the N-terminal kinase domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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