Thermo Fisher Scientific LPAP Polyclonal Antibody
Thermo Fisher Scientific의 LPAP Polyclonal Antibody는 인간 단백질에 반응하는 토끼 IgG 기반 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 1 mg/mL 농도와 안정적인 저장 조건을 제공합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 156 to 206 of human Lymphocyte Phosphatase-Associated Phosphoprotein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
MSK-1 is a mitogen and stress-activated protein kinase-1 belonging to the AGC family of kinases, structurally related to the ribosomal p70 S6 kinase subfamily.
MSK-1 can be activated by ERK1/2 and SAPK2/p38 MAP kinase and is required for phosphorylation of CREB, ATF1, H3, and HMG-14 in response to mitogen and stress.
Similar to RSK, MSK-1 contains two kinase domains (N-terminal and C-terminal). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK-1 autophosphorylates on at least five sites, including Ser212 and Ser376, which are essential for catalytic activity of the N-terminal kinase domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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