Thermo Fisher Scientific MARCKS Polyclonal Antibody
MARCKS 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot과 Immunocytochemistry에 사용 가능. 인간, 생쥐, 랫트 반응성. 액상 형태로 1 mg/mL 농도, PBS/glycerol buffer에 보관. 세포 이동성 및 막 관련 연구에 적합.
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Thermo Fisher Scientific MARCKS Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MARCKS (Accession P29966), corresponding to amino acid residues T133–E183 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853889 |
Product Specific Information
Antibody detects endogenous levels of total MARCKS.
Target Information
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and acts as an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and the plasma membrane, leading to cytoplasmic localization. It is involved in cell motility, phagocytosis, membrane trafficking, and mitogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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