Thermo Fisher Scientific Desmoglein 4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Desmoglein 4. Recombinant protein control fragment (Product #RP-101507). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Desmoglein 4,uniProtId:Q86SJ6-1,ncbiNodeId:9606,antigenRange:415-509,antigenLength:1040,antigenImageFileName:PA5-63728_Desmoglein_4_Q86SJ6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63728_Desmoglein_4_Q86SJ6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640536

Product Specific Information

Immunogen sequence: DLDTGNPATD VRYIIGHDAG SWLKIDSRTG EIQFSREFDK KSKYIINGIY TAEILAIDDG SGKTATGTIC IEVPDINDYC PNIFPERRTI CIDSP

Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 77%.

Target Information

Desmoglein proteins are cadherin-type cell adhesion molecules. Desmoglein 4 (dsg4) shares 41% identity with human desmoglein 1, 37% with human desmoglein 2 and 50% with human desmoglein 3. A type I membrane protein of the cadherin protein family, dsg4 is expressed in salivary gland, suprabasal epidermis, hair follicle, testis, prostate and skin. In the hair follicle, dsg4 is an important mediator of keratinocyte cell adhesion and coordinates the transition from proliferation to differentiation. The human DSG4 gene is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.