Thermo Fisher Scientific Desmoglein 4 Polyclonal Antibody
Human Desmoglein 4을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 실험에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 버퍼에 40% 글리세롤 포함. 연구용으로만 사용 가능.
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- PA563728
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Desmoglein 4. Recombinant protein control fragment (Product #RP-101507) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640536 |
Product Specific Information
Immunogen sequence:
DLDTGNPATD VRYIIGHDAG SWLKIDSRTG EIQFSREFDK KSKYIINGIY TAEILAIDDG SGKTATGTIC IEVPDINDYC PNIFPERRTI CIDSP
- Highest antigen sequence identity to the following orthologs:
- Mouse: 77%
- Rat: 77%
Target Information
Desmoglein proteins are cadherin-type cell adhesion molecules.
Desmoglein 4 (DSG4) shares 41% identity with human desmoglein 1, 37% with desmoglein 2, and 50% with desmoglein 3.
It is a type I membrane protein expressed in salivary gland, suprabasal epidermis, hair follicle, testis, prostate, and skin.
In the hair follicle, DSG4 mediates keratinocyte adhesion and coordinates the transition from proliferation to differentiation.
The human DSG4 gene comprises 16 exons spanning approximately 37 kb on chromosome 18q12, located between DSG1 and DSG3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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