Thermo Fisher Scientific DOK7 Polyclonal Antibody
DOK7 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC(P), ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 용액 형태로 제공됩니다. 인간 DOK7 단백질 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DOK7. Recombinant protein control fragment (Product #RP-101684). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640747 |
Product Specific Information
Immunogen sequence:
SSLDVWRATD ELGSLLSLPA AGAPEPSLCT CLPGTVEYQV PTSLRAHYDT PRSLCLAPRD HS
Highest antigen sequence identity to the following orthologs:
- Mouse: 75%
- Rat: 75%
Target Information
The protein encoded by this gene is essential for neuromuscular synaptogenesis. It functions in aneural activation of muscle-specific receptor kinase (MuSK), which is required for postsynaptic differentiation and acetylcholine receptor clustering in myotubes. This protein can also induce autophosphorylation of MuSK.
Mutations in this gene cause familial limb-girdle myasthenia autosomal recessive (congenital myasthenic syndrome type 1B).
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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