Thermo Fisher Scientific PIK3R4 Monoclonal Antibody (1B5)
PIK3R4 단백질을 인식하는 Mouse Monoclonal Antibody(클론 1B5). Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Human 반응성, Affinity chromatography로 정제, PBS buffer에 보존. 연구용으로만 사용 가능.
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Thermo Fisher Scientific PIK3R4 Monoclonal Antibody (1B5)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.6 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B5 |
| Immunogen | PIK3R4 (NP_055417, 1259–1358 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
AGSDMKIRFW DLAYPERSYV VAGSTSSPSV SYYRKIIEGT EVVQEIQNKQ KVGPSDDTPR RGPESLPVGH HDIITDVATF QTTQGFIVTA SRDGIVKVWK
Target Information
Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different complex forms are believed to play roles in multiple membrane trafficking pathways:
- PI3KC3-C1: involved in initiation of autophagosomes
- PI3KC3-C2: involved in maturation of autophagosomes and endocytosis
Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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