Thermo Fisher Scientific TSN Monoclonal Antibody (OTI1B5), TrueMAB
인간 TSN 단백질을 인식하는 OTI1B5 클론의 마우스 단일클론 항체. Western blot과 IHC(P) 적용 가능. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 버퍼에 보관. 연구용으로만 사용.
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Applications
- Western Blot (WB): 1:500–1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–51 of human TSN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Translin is a DNA-binding protein that specifically recognizes conserved target sequences at the breakpoint junctions of chromosomal translocations. It forms a multimeric structure responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that, in combination with the binding partner Trax, Translin binds RNA and mediates trafficking in neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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