Thermo Fisher Scientific Pan RhO Polyclonal Antibody
Rho 계열 GTP 결합 단백질을 인식하는 sheep polyclonal antibody로, Western blot과 IHC에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, 동결 건조 형태로 제공됩니다. 세포 형태와 이동성 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Miscellaneous (PubMed)
- View 3 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 50–100 of human Rho-related GTP-binding proteins (RhOA, RhOB, RhOC, RhOF, RhOQ) and RAC1, RAC2, RAC3, CDC42 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: RhO family.
Target Information
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades.
Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility.
The protein encoded by this gene is prenylated at its C-terminus and localizes to the cytoplasm and plasma membrane.
It is important in cell locomotion, and its overexpression is associated with tumor cell proliferation and metastasis.
Multiple alternatively spliced variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명 예시)
- OSC00070W-100UL_Rho_Pan_P08134-1_Sheep.svg
- OSC00070W-100UL_Rho_Pan_P08134-1_Sheep_PDP.jpeg
- OSC00070W-100UL_Rho_Pan_P61586-1_Sheep.svg
- OSC00070W-100UL_Rho_Pan_P61586-1_Sheep_PDP.jpeg
- OSC00070W-100UL_Rho_Pan_P62745-1_Sheep.svg
- OSC00070W-100UL_Rho_Pan_P62745-1_Sheep_PDP.jpeg
- OSC00070W-100UL_Rho_Pan_P17081-1_Sheep.svg
- OSC00070W-100UL_Rho_Pan_P17081-1_Sheep_PDP.jpeg
- OSC00070W-100UL_Rho_Pan_Q9HBH0-1_Sheep.svg
- OSC00070W-100UL_Rho_Pan_Q9HBH0-1_Sheep_PDP.jpeg
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