Thermo Fisher Scientific Pan RhO Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:2,000

-

Immunohistochemistry (IHC)

1:300-1:2,000

-

Miscellaneous PubMed (Misc)

-

View 3 publications 3 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Not Applicable

Host/Isotype

Sheep / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from aa region 50-100 of human Rho-related GTP-binding proteins (RhOA, RhOB, RhOC, RhOF, RhOQ) and RAC1, RAC2, RAC3 and CDC42 conjugated to an immunogenic carrier protein was used as the antigen if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Rho Pan,uniProtId:P08134-1,ncbiNodeId:9606,antigenRange:50-100,antigenLength:193,antigenImageFileName:OSC00070W-100UL_Rho_Pan_P08134-1_Sheep.svg,antigenImageFileNamePDP:OSC00070W-100UL_Rho_Pan_P08134-1_Sheep_PDP.jpeg,sortOrder:1},{targetFamily:Rho Pan,uniProtId:P61586-1,ncbiNodeId:9606,antigenRange:50-100,antigenLength:193,antigenImageFileName:OSC00070W-100UL_Rho_Pan_P61586-1_Sheep.svg,antigenImageFileNamePDP:OSC00070W-100UL_Rho_Pan_P61586-1_Sheep_PDP.jpeg,sortOrder:2},{targetFamily:Rho Pan,uniProtId:P62745-1,ncbiNodeId:9606,antigenRange:50-100,antigenLength:196,antigenImageFileName:OSC00070W-100UL_Rho_Pan_P62745-1_Sheep.svg,antigenImageFileNamePDP:OSC00070W-100UL_Rho_Pan_P62745-1_Sheep_PDP.jpeg,sortOrder:3},{targetFamily:Rho Pan,uniProtId:P17081-1,ncbiNodeId:9606,antigenRange:50-100,antigenLength:205,antigenImageFileName:OSC00070W-100UL_Rho_Pan_P17081-1_Sheep.svg,antigenImageFileNamePDP:OSC00070W-100UL_Rho_Pan_P17081-1_Sheep_PDP.jpeg,sortOrder:4},{targetFamily:Rho Pan,uniProtId:Q9HBH0-1,ncbiNodeId:9606,antigenRange:50-100,antigenLength:211,antigenImageFileName:OSC00070W-100UL_Rho_Pan_Q9HBH0-1_Sheep.svg,antigenImageFileNamePDP:OSC00070W-100UL_Rho_Pan_Q9HBH0-1_Sheep_PDP.jpeg,sortOrder:5}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: RhO family.

Target Information

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.