Thermo Fisher Scientific SOD3 Monoclonal Antibody (4GG11G6), APC
SOD3 단백질을 인식하는 APC 결합 단클론 항체로, Western blot, IHC, ICC/IF, ELISA 등에 사용 가능. 인간, 마우스, 랫트, 기니피그에 반응하며 Protein G로 정제됨. 4°C 보관, 형광 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Guinea pig, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4GG11G6 |
| Immunogen | Human extracellular SOD purified from aortas |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931677 |
Available Formats
- Unconjugated (MA5-27661)
- FITC (MA5-45224)
- PE (MA5-45226)
- PerCP (MA5-45225)
- Custom conjugation available on request
Product Specific Information
1 µg/mL of MA5-45223 was sufficient for detection of extracellular SOD (EC-SOD) in 20 µg of human cartilage lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects extracellular SOD at approximately 35 kDa.
Target Information
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. It is widely expressed in human tissues and shows increased expression in actively dividing cells such as testis, thymus, fetal liver, and carcinomas. The protein localizes to the nucleus and promotes stability and nuclear accumulation of transcriptionally active p53, phosphorylating Thr18 of p53 to reduce ubiquitination. It may regulate cell proliferation and also phosphorylates histone, casein, and transcription factors ATF2 and c-JUN.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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