Thermo Fisher Scientific LGP2 Polyclonal Antibody
LGP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, ICC/IF, ELISA에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며 고순도 친화 크로마토그래피 정제 제품입니다. 항바이러스 선천면역 연구용으로 최적화되어 있습니다.
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Thermo Fisher Scientific LGP2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 389–678 of human DHX58 (NP_077024.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 9.77 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855046 |
Product Specific Information
Immunogen sequence:
QQQGLQTVDI RAQLLIGAGN SSQSTHMTQR DQQEVIQKFQ DGTLNLLVAT SVAEEGLDIP HCNVVVRYGL LTNEISMVQA RGRARADQSV YAFVATEGSR ELKRELINEA LETLMEQAVA AVQKMDQAEY QAKIRDLQQA ALTKRAAQAA QRENQRQQFP VEHVQLLCIN CMVAVGHGSD LRKVEGTHHV NVNPNFSNYY NVSRDPVVIN KVFKDWKPGG VISCRNCGEV WGLQMIYKSV KLPVLKVRSM LLETPQGRIQ AKKWSRVPFS VPDFDFLQHC AENLSDLSLD
Target Information
Anti-viral innate immune responses are triggered by pathogen-associated molecular patterns, such as intracellular nucleic acids resulting from viral infections. These responses represent the first line of defense against infectious organisms.
Toll-like receptors (TLR) 3, 7, 8, and 9 act as transmembrane pattern recognition receptors detecting foreign nucleic acids.
Proteins like RIG-1 and MDA5, members of the CARD-helicase family, function in the cytoplasm.
LGP2, similar to RIG-1 and MDA5 but lacking a CARD domain, is believed to regulate intracellular antiviral signaling via negative feedback.
At least four isoforms of LGP2 are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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