Thermo Fisher Scientific GTF3C4 Monoclonal Antibody (OTI4A1), TrueMAB
GTF3C4 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB 및 IHC(P) 실험에 적합. Human, Mouse, Rat 등 다양한 종에 반응. 동결건조 형태로 제공되며, 고순도의 친화 크로마토그래피 정제 제품. RNA polymerase III 관련 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 583–822 of human GTF3C4 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Essential for RNA polymerase III to synthesize small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA.
Exhibits histone acetyltransferase (HAT) activity with specificity for free and nucleosomal H3.
May cooperate with GTF3C5 to recruit TFIIIB and RNA polymerase III through interactions with BRF1, POLR3C, and POLR3F.
Localized near the A box. [UniProt]
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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