Thermo Fisher Scientific MCM3 Polyclonal Antibody
Thermo Fisher Scientific의 MCM3 Polyclonal Antibody는 인간 MCM3 단백질을 인식하는 염소 유래 다클론 항체입니다. Western blot 및 IHC에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C에서 보관하며 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MCM3 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 500 and 550 of human Minichromosome Maintenance 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC on FFPE tissue sections, epitope retrieval with citrate buffer (pH 6.0) is recommended
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance (MCM) proteins involved in the initiation of eukaryotic genome replication. The hexameric complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and plays a role in replication fork formation and recruitment of other DNA replication-related proteins.
MCM3 is a subunit of the MCM2–7 complex and interacts directly with MCM5/CDC46. It also interacts with MCM3AP, a chromatin-associated acetyltransferase, which acetylates MCM3, thereby inhibiting DNA replication initiation and cell cycle progression.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.