
Thermo Fisher Scientific LLGL2 Polyclonal Antibody
LLGL2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. IHC(P)에서 1:25–1:100 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 버퍼에 보관. 인간 단백질 반응성, 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the C-terminal of human lethal giant larvae homolog 2 (Drosophila) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636274 |
Product Specific Information
This antibody detects endogenous levels of total LLGL2 protein.
Target Information
LLGL1 is a protein similar to a tumor suppressor in Drosophila. It is part of the cytoskeletal network and associates with nonmuscle myosin II heavy chain and a kinase that phosphorylates it at serine residues. The LLGL1 gene is located within the Smith-Magenis syndrome region on chromosome 17.
LLGL2 is homologous to the Drosophila lethal (2) giant larvae protein. In flies, its localization of cell fate determinants is regulated by atypical protein kinase C (aPKC). In humans, LLGL2 interacts with aPKC-containing complexes and localizes cortically in mitotic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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