Thermo Fisher Scientific Resistin Monoclonal Antibody (D2)
Thermo Fisher Scientific의 Resistin Monoclonal Antibody (D2)는 인간 Resistin 단백질을 인식하는 Mouse IgG1 항체입니다. WB 및 IHC(P) 실험에 적합하며, Protein A/G로 정제된 액상 형태입니다. 고순도, 높은 특이성, 안정적 보관(-20°C) 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.01–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–30 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | D2 |
| Immunogen | Recombinant protein Resistin (amino acids 17–108 of the target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899151 |
Target Information
Adipose tissue acts as an energy reserve and produces several key proteins such as lipoprotein lipase (LPL), leptin, Acrp30, perilipin, and resistin.
Resistin, also known as Adipocyte Secreted Factor (ADSF) and FIZZ3, is a cytokine secreted by adipocytes. It plays potential roles in type 2 diabetes and insulin resistance.
In obese, diabetic mice, serum resistin levels are elevated, antagonizing insulin activity. Studies indicate that resistin gene expression depends on C/EBP alpha and is influenced by CBP and p300 coactivators through histone acetylation. PPAR gamma and RXR ligands have been shown to downregulate resistin expression in adipocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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