Thermo Fisher Scientific LOX Polyclonal Antibody
LOX 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. Western blot 등 연구용으로 사용되며, 인간 시료에 반응합니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관합니다. 세포 외 기질 형성과 암 전이 연구에 적합합니다.
- 카탈로그번호
- PA5143229
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-STAYRADVRDYDHR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933868 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_002308.2; NP_001171573.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Lysyl oxidase (LOX) is a copper-containing amine oxidase that oxidizes primary amine substrates to reactive aldehydes. It plays a crucial role in extracellular matrix formation and repair. LOX also has diverse biological functions, including developmental regulation, tumor suppression, cell motility, and cellular senescence. The secreted form of LOX contributes to the invasive properties of hypoxic human cancer cells and is essential for hypoxia-induced metastasis, making it a valuable therapeutic target for preventing and treating metastases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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