Thermo Fisher Scientific Acetyl-NFkB p65 (Lys314, Lys315) Polyclonal Antibody
NFκB p65 단백질의 Lys314/315 아세틸화 형태를 특이적으로 검출하는 폴리클로날 항체. Western blot 및 IHC(Paraffin) 실험에 적합. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NFκB-p65 around the acetylation site of Lys314/315 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899332 |
Product Specific Information
This antibody detects endogenous levels of NFκB-p65 only when acetylated at Lys314/315.
Target Information
Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and located on chromosome 11 in humans. NF-kB p65, also known as RelA, belongs to the Rel family of proteins and forms a heterodimer with p50 or p52 subunits. Upon TNFα stimulation, IKK phosphorylates IκB, leading to its proteasomal degradation. NF-kB p65 plays a crucial role in transcription of the immunoglobulin kappa gene in mature B-lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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