Thermo Fisher Scientific Crotonyl-HIST1H2BC (Lys20) Polyclonal Antibody
Human Histone H2B Crotonyl-Lys20 특이적 폴리클로날 항체로, WB, ICC/IF, ChIP 등 다양한 응용에 사용 가능. Rabbit IgG 기반, 항원 친화 크로마토그래피로 정제됨. 고농도 액상 형태로 안정적이며, 연구용으로만 사용.
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Thermo Fisher Scientific Crotonyl-HIST1H2BC (Lys20) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:100–1:1,000 | |
| Immunocytochemistry (ICC/IF) | 1:10–1:100 | |
| ChIP assay (ChIP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around site of Crotonyl-Lys (20) derived from Human Histone H2B type 1-C/E/F/G/I |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.161 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2902106 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher-order structures. The protein has antibacterial and antifungal antimicrobial activity. The main transcript variant of this gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. This transcript variant lacks a polyA tail but instead contains a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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