Thermo Fisher Scientific TrkC Monoclonal Antibody (7H6)
Human NTRK3(TrkC) 단백질을 특이적으로 인식하는 mouse monoclonal antibody로, WB, IHC, ELISA 등에 사용 가능. 비결합형 액상 형태이며 sodium azide 함유. 신경계 관련 단백질 연구에 적합.
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Thermo Fisher Scientific TrkC Monoclonal Antibody (7H6)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7H6 |
| Immunogen | Purified recombinant extracellular fragment of human NTRK3 (aa32–429) fused with hIgGFc tag expressed in HEK293 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10989345 |
Product Specific Information
MA5-15543 targets NTRK3 in indirect ELISA, IHC, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant extracellular fragment of human NTRK3 (aa32–429) fused with hIgGFc tag expressed in HEK293 cells.
MA5-15543 detects NTRK3, which has a predicted molecular weight of approximately 94 kDa.
Target Information
NTRK3 (TRKC) belongs to the neurotrophic factor family central to the development and maintenance of the mammalian nervous system. Known substrates for TRK receptors include SHC, PI-3 kinase, and PLCG1. Isoforms differ in signaling properties. The protein is widely expressed, mainly in nervous tissue. Isoform B is expressed more abundantly in the adult brain than in the fetal brain. TRKC undergoes ligand-mediated auto-phosphorylation and contains two immunoglobulin-like C2-type domains and two leucine-rich repeats (LRR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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