Thermo Fisher Scientific PAK6 Polyclonal Antibody
PAK6 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, 인체 시료에 반응합니다. IHC(P)에서 4.8 µg/mL 농도로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 용액에 0.1% sodium azide가 포함되어 있으며, 연구용으로만 사용됩니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 4.8 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from Linker domain of human PAK6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551454 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Orangutan, Gibbon (100%)
- Monkey, Panda, Bovine (95%)
- Marmoset, Rat, Elephant, Bat, Dog, Rabbit, Horse (89%)
Target Information
PAK6 is a serine/threonine kinase expressed in the testis and prostate. It associates with both the estrogen and androgen receptors. The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac.
They are divided into two groups:
- Group 1 (PAK1, 2, 3): Activated by Cdc42/Rac binding and involved in gene transcription, apoptosis, and cell morphology/motility.
- Group 2 (PAK4, 5, 6): Not activated by Cdc42/Rac binding; may be activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting a role in stress response signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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