Thermo Fisher Scientific RASSF8 Polyclonal Antibody
RASSF8 단백질을 인식하는 Rabbit Polyclonal 항체로, 인체 시료에 반응합니다. IHC(P) 실험에 1:50–1:200 희석 비율로 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 용액 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RASSF8. Recombinant protein control fragment (Product #RP-102815). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646344 |
Product Specific Information
Immunogen sequence:
TEFKQKVLNN CKTTADELKK LIRLQTEKLQ SIEKQLESNE IEIRFWEQKY NSNLEEEIVR LEQKIKRNDV EIEEEEFWEN ELQIE
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 82%
Target Information
RASSF8 encodes a member of the Ras-association domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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