Thermo Fisher Scientific DEDD Polyclonal Antibody
DEDD 단백질을 표적으로 하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간과 마우스 반응성이 있으며, 항원 친화 크로마토그래피로 정제된 고순도 항체입니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific DEDD Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human DEDD (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2735713 |
Product Specific Information
- Positive Control: Mouse leukocyte treated with CFA
- Predicted Reactivity: Rat (98%), Xenopus laevis (86%), Rhesus Monkey (99%), Bovine (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
DEDD encodes a protein containing a death effector domain (DED), a protein-protein interaction domain shared among adaptors, regulators, and executors of the programmed cell death pathway. Overexpression of DEDD induces weak apoptosis. Upon stimulation, DEDD translocates from cytoplasm to nucleus and colocalizes with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been identified.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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