Thermo Fisher Scientific ALDH1A1 (Aldehyde Dehydrogenase 1A1) Monoclonal Antibody (ALDH1A1, 4793)
인간 ALDH1A1 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot, IHC, Peptide Array에 사용 가능. 단백질 A/G로 정제된 액상 형태이며 PBS buffer에 보존. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ALDH1A1, 4793 |
| Immunogen | Recombinant full-length human ALDH1A1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
ALDH1A1 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms—cytosolic and mitochondrial—can be distinguished by electrophoretic mobility, kinetic properties, and subcellular localization. Most Caucasians have both isoforms, while approximately 50% of Orientals have only the cytosolic isoform, lacking the mitochondrial isozyme. This difference may be related to the higher incidence of acute alcohol intoxication among Orientals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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