Thermo Fisher Scientific UBA52 Polyclonal Antibody
UBA52 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, Western blot과 Immunocytochemistry에 적합합니다. 인간, 마우스, 영장류 시료에 반응하며, 고순도 친화 크로마토그래피로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5102973
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific UBA52 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human UBA52 (Accession P62987), corresponding to amino acid residues C96–K128 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852347 |
Product Specific Information
Antibody detects endogenous levels of total UBA52.
Target Information
Ubiquitin is a highly conserved protein that plays a major role in targeting cellular proteins for degradation by the 26S proteasome. It is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein.
The UBA52 gene encodes a fusion protein composed of ubiquitin at the N-terminus and ribosomal protein S27a at the C-terminus. When expressed in yeast, this protein is post-translationally processed to generate free ubiquitin monomer and ribosomal protein S27a.
Ribosomal protein S27a is a component of the 40S subunit of the ribosome, belongs to the S27AE family, contains C4-type zinc finger domains, and is located in the cytoplasm. Pseudogenes derived from this gene exist in the genome.
Similarly, ribosomal proteins L40 and S30 are synthesized as fusion proteins with ubiquitin or ubiquitin-like proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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