Thermo Fisher Scientific CYP3A5 Polyclonal Antibody
CYP3A5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 검증됨. 인간, 마우스, 랫트 반응성. Affinity chromatography로 정제된 액상 항체이며, PBS/glycerol buffer에 보관. 약물 대사 관련 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CYP3A5 (Accession P20815), corresponding to amino acid residues N237–H287 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852351 |
Product Specific Information
This antibody detects endogenous levels of total CYP3A5.
Target Information
CYP3A5 is a member of the cytochrome P450 superfamily of enzymes. These monooxygenases catalyze reactions involved in drug metabolism and the synthesis of cholesterol, steroids, and other lipids. The protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and certain pharmacological agents. CYP3A5 metabolizes drugs such as nifedipine and cyclosporine, as well as steroid hormones including testosterone, progesterone, and androstenedione.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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