Thermo Fisher Scientific LRP12 Isoform A Precursor Polyclonal Antibody
Thermo Fisher Scientific의 LRP12 Isoform A Precursor 폴리클로날 항체로, Human 시료에 반응하며 Western blot에 적합합니다. Rabbit IgG 기반 비결합 항체로 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 795–859 of LRP12 (Uniprot ID: Q9Y561) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153523 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji
- Predicted reactivity: Pig (100%), Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
Members of the LDL receptor gene family, including LDLR, LRP1, Megalin (GP330), VLDLR, and ApoER2, are characterized by cysteine-rich class A repeats, EGF-like repeats, YWTD repeats, and an O-linked sugar domain.
LRP12 (also designated ST7) is a member of this family, involved in internalization of lipophilic molecules and/or signal transduction. It interacts with RACK1, MADHIP, and Integrin beta-1-binding protein 3, and is widely expressed in heart, skeletal muscle, brain, lung, placenta, and pancreas. Overexpression may be associated with oral tumors, suggesting a potential oncogenic role.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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