Thermo Fisher Scientific LRP12 Isoform A Precursor Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to a region within amino acids 795 and 859 of LRP12 (Uniprot ID#Q9Y561) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LRP12 Isoform A Precursor,uniProtId:Q9Y561-1,ncbiNodeId:9606,antigenRange:795-859,antigenLength:859,antigenImageFileName:PA5-21956_LRP12_Isoform_A_Precursor_Q9Y561-1_Rabbit.svg,antigenImageFileNamePDP:PA5-21956_LRP12_Isoform_A_Precursor_Q9Y561-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

0.1M tris glycine, pH 7, with 10% glycerol

Contains

0.01% thimerosal

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_11153523

Product Specific Information

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji.

Predicted reactivity: Pig (100%), Rhesus Monkey (100%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Members of the LDL receptor gene family, including LDLR (low density lipoprotein receptor), LRP1 (low density lipoprotein related protein), Megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2 are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. LRP12, also designated ST7, is a member of the LDLR family that is thought to be involved in the internalization of lipophilic molecules and/or signal transduction. LRP12 has been shown to interact with RACK1, MADHIP and Integrin beta-1-binding protein 3. It is widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. Overexpression of LRP12 may be associated with oral tumors, therefore implicating LRP12 as a potential oncogene.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.