Thermo Fisher Scientific RAMP1 Polyclonal Antibody
RAMP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 생쥐, 랫트에 반응하며 Western blot에 적합. 항원 친화 크로마토그래피로 정제된 액상 제품으로, 4°C 또는 -20°C 보관.
- 카탈로그번호
- PA521954
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 84–148 of RAMP1 (Uniprot ID#O60894) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.87 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153424 |
Product Specific Information
- Recommended positive controls: HepG2, mouse brain, rat brain
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs).
RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus.
They are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane.
CRLR can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which RAMP family members are expressed.
In the presence of RAMP1, CRLR functions as a CGRP receptor.
RAMP1 is involved in terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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