CacheBy
Thermo Fisher Scientific FCHSD2 Polyclonal Antibody
원본

Thermo Fisher Scientific FCHSD2 Polyclonal Antibody

상품 한눈에 보기

Human FCHSD2 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보존. 세포 내 수용체 엔도사이토시스 연구에 적합.

카탈로그번호
PA558433
판매단위
pk
카탈로그 보기

카탈로그

1개 옵션
회원가입 없이 바로 구매하세요
가입하지 않아도 비회원가로 구매하실 수 있습니다.
마지막 업데이트 2025. 08. 02. 오전 06:15
Thermo Fisher Scientific PA558433 FCHSD2 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
782,000원VAT 포함 860,200원

Thermo Fisher Scientific · Thermo Fisher Scientific FCHSD2 Polyclonal Antibody

Thermo Fisher Scientific FCHSD2 Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution
Immunohistochemistry (Paraffin) (IHC (P)) 1:200–1:500
Immunocytochemistry (ICC/IF) 0.25–2 µg/mL

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Recombinant protein corresponding to Human FCHSD2 (Product #RP-97343)
Conjugate Unconjugated
Form Liquid
Concentration 0.2 mg/mL
Purification Antigen affinity chromatography
Storage Buffer PBS, pH 7.2, with 40% glycerol
Contains 0.02% sodium azide
Storage Conditions Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles.
Shipping Conditions Wet ice
RRID AB_2641575

Product Specific Information

Immunogen sequence:
LENSSKVVRD YNLQLFLQEN AVFHKPQPFQ FQPCDSDTSR QLESETGTTE EHSLNKEARK WATRVAREHK NIVHQQRVLN DLECHGAAVS EQSRA

Highest antigen sequence identity to the following orthologs:

  • Mouse: 97%
  • Rat: 98%

Target Information

Adapter protein involved in endocytosis via clathrin-coated pits.

  • Contributes to internalization of cell surface receptors (e.g., integrin ITGB1, transferrin receptor).
  • Promotes EGFR endocytosis and down-regulation of EGFR signaling in cancer cells.
  • Recruited during mid-to-late pit assembly stages for normal pit progression.
  • Binds membranes enriched in phosphatidylinositol 3,4-bisphosphate or phosphatidylinositol 3,4,5-trisphosphate.
  • Promotes actin polymerization via WAS/WASL interaction and Arp2/3 complex activation.
  • Does not promote actin polymerization without membranes.
    (Source: UniProt)

For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.

제품 이미지

Immunogen diagram
Product image

Thermo Fisher Scientific 상품 둘러보기

전체보기

문의

0

아직 등록된 문의가 없어요.