Thermo Fisher Scientific PTGES3 Monoclonal Antibody (OTI2F2), TrueMAB
인간 PTGES3 단백질을 인식하는 마우스 단클론 항체로 Western blot에 최적화됨. 1 mg/mL 농도의 액상 형태이며, 친화 크로마토그래피로 정제됨. PBS, BSA, 글리세롤 완충액에 보관되며 -20°C에서 안정적. 연구용으로만 사용 가능.
- 카탈로그번호
- TA803290
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F2 |
| Immunogen | Full length human recombinant protein of human PTGES3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Steroid receptors are ligand-dependent intracellular proteins that regulate transcription of specific genes by binding to DNA sequences after activation by hormones. Before activation, steroid receptors form complexes with various proteins such as HSP70, HSP90, and immunophilins (FKBP52, FKBP54, CyP-40), as well as p23, p60, and p48.
p23, together with HSP70, HSP90, and p60, associates transiently with the progesterone receptor (PR). The cloned human p23 encodes a 160-amino-acid protein highly conserved across species and lacking homology to other known proteins. It is an acidic phosphoprotein with a C-terminal domain rich in aspartic acid and multiple phosphorylation sites. In vitro, p23 binds to HSP90 and is essential for HSP90 and CyP-40 binding to PR, suggesting an important role in PR function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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