Thermo Fisher Scientific beta Amyloid Monoclonal Antibody (BAM-10)
Alzheimer 연구용 베타 아밀로이드 단클론 항체(BAM-10). 인간 및 생쥐 반응성. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 비결합형 액상 포맷, 4°C 보관.
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Thermo Fisher Scientific beta Amyloid Monoclonal Antibody (BAM-10)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
| Immunocytochemistry (ICC/IF) | 1:200 | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BAM-10 |
| Immunogen | Synthetic peptide conjugated to KLH, corresponding to amino acids 1–40 of beta Amyloid |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_1954846 |
Product Specific Information
Recommended positive control: Brain tissue.
Target Information
Amyloid beta peptide (Abeta/Beta-amyloid) is the major constituent of amyloid plaques in the brains of individuals afflicted with Alzheimer’s disease.
Abeta peptide (40–43 amino acids) is generated from the beta-amyloid precursor protein (beta APP) through sequential cleavage by beta-secretase (BACE) and gamma-secretase.
Gamma-secretase, a multi-subunit complex containing presenilin-1 and -2, and nicastrin, modulates production of the amyloid beta peptide.
Abeta is found in amyloid cores, neuritic plaques, and neurofibrillary tangles associated with Alzheimer’s disease, Lewy body dementia, Down’s syndrome, Dutch-type amyloidosis, cerebral amyloid angiopathy, and Guam Parkinson-Dementia complex.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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