Thermo Fisher Scientific Caspase 7 Monoclonal Antibody (B4-G2)

Thermo Fisher Scientific Caspase 7 Monoclonal Antibody (B4-G2)

Applications and Tested Dilution

• Western Blot (WB): 0.5–2 µg/mL
• Immunoprecipitation (IP): 4–10 µg/mL

Product Specifications

Product Specific Information

MA1-91217 detects Caspase 7 from mouse, rat, and human samples.

Target Information

Caspase 7 is a member of the cysteine protease family, divided into apoptotic and inflammatory subfamilies.

• Apoptotic subfamily: Includes initiator and executioner caspases. Caspase 7 acts as an executioner caspase, activated by initiator caspases to cleave cellular substrates leading to cell death.
• Gene characteristics: Alternative splicing of Caspase-7 mRNA produces three distinct isoforms. Caspase-7 activity can be directly inhibited by XIAP expression.
• Associated diseases: Type 1 Diabetes Mellitus 17, Aleutian Mink Disease.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

Usage Restriction

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.