Thermo Fisher Scientific RIOK3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RIOK3. Recombinant protein control fragment (Product #RP-101004). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RIOK3,uniProtId:O14730-1,ncbiNodeId:9606,antigenRange:26-147,antigenLength:519,antigenImageFileName:PA5-55005_RIOK3_O14730-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55005_RIOK3_O14730-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646578

Product Specific Information

Immunogen sequence: IPQNTISCSL ADVMSEQLAK ELQLEEEAAV FPEVAVAEGP FITGENIDTS SDLMLAQMLQ MEYDREYDAQ LRREEKKFNG DSKVSISFEN YRKVHPYEDS DSSEDEVDWQ DTRDDPYRPA KP

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.

Target Information

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. SUDD, also known as RIOK3 (RIO kinase 3), is a 519 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Expressed in a variety of tissues, SUDD catayzes the ATP-dependent phosphorylation of target proteins, thereby influencing signaling events throughout the cell. SUDD is expressed as two isoforms due to alternative splicing events.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.