Thermo Fisher Scientific SIKE Polyclonal Antibody
SIKE 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 적합. 인간 시료 반응성, 항원 친화 크로마토그래피 정제, 고순도 액상 형태. 바이러스 및 TLR3 신호 억제 연구에 활용 가능.
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Thermo Fisher Scientific SIKE Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC(P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SIKE. Recombinant protein control fragment (Product #RP-93991) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647306 |
Product Specific Information
Immunogen sequence:
ESLVDQSAAL HRRVAAMREA GTALPDQYQE DASDMKDMSK YKPHILLSQE NTQIRDLQQE NRELWISLEE HQDALEL
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 94%
Target Information
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3 activation. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3, and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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