Thermo Fisher Scientific DENND4C Polyclonal Antibody
DENND4C 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 최적화된 검증된 항체로 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 기반 저장 버퍼 포함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DENND4C. Recombinant protein control fragment (Product #RP-91444) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640519 |
Product Specific Information
Immunogen sequence:
PSGIFDVNSR KSSTGSISNV LFSTQDPVED AVFGEATNLK KNGDRGEKRQ KHFPERSCSF SSESRAGMLL KKSSLDSNSS EMAIMMGADA KILTAALTCP KTSLLHIART HSFENVSCHL PDSRTCMSES TW
Highest antigen sequence identity to the following orthologs:
- Mouse: 83%
- Rat: 86%
Target Information
DENND4C is a guanine nucleotide exchange factor (GEF) activating RAB10. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. This activation stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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