Thermo Fisher Scientific Phospho-BAD (Ser155) Monoclonal Antibody (27AT381)
Phospho-BAD (Ser155) 단백질의 인산화 상태를 검출하는 mouse monoclonal antibody입니다. Western blot에 적합하며, Human과 Mouse 시료에 반응합니다. Protein G로 정제된 액상 제품으로, 장기 보관 시 -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 27AT381 |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Ser155 of mouse Bad |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10982347 |
Target Information
The protein encoded by BAD is a member of the BCL-2 family, which regulates programmed cell death. This protein promotes apoptosis by forming heterodimers with BCL-xL and BCL-2, reversing their anti-apoptotic function. Its proapoptotic activity is controlled by phosphorylation, involving kinases such as AKT and MAP kinase, and phosphatase calcineurin. Alternative splicing results in two transcript variants encoding the same isoform.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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