Thermo Fisher Scientific DRG1 Polyclonal Antibody

Thermo Fisher Scientific DRG1 Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: VLKPLGHKKI IENELEGFGI RLNSKPPNIG FKKKDKGGIN LTATCPQSEL
• Storage guidance:
  • Short term: 2–8°C up to 1 week
  • Long term: Store at -20°C in small aliquots to prevent freeze-thaw cycles
• Predicted homology:
  Cow: 100% | Dog: 100% | Guinea Pig: 100% | Horse: 100% | Human: 100% | Mouse: 100% | Rabbit: 100% | Rat: 100% | Yeast: 91% | Zebrafish: 86%

Target Information

Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP (PubMed:29915238, PubMed:23711155).
Has intrinsic GTPase activity stimulated by ZC3H15/DFRP1 binding, likely increasing affinity for potassium ions (PubMed:23711155).
When hydroxylated at C-3 of Lys-22 by JMJD7, may bind RNA and play a role in translation (PubMed:19819225, PubMed:29915238).
Binds to microtubules and promotes polymerization and stability required for mitotic spindle assembly during prophase to anaphase transition.
GTPase activity is not necessary for these microtubule-related functions (PubMed:28855639).
[UniProt]

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.