Thermo Fisher Scientific NR4A2 Monoclonal Antibody (1D9)
NR4A2(Nurr1) 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, 인간 시료에 반응합니다. Western blot 및 ELISA에 사용 가능하며, Affinity chromatography로 정제된 액상 형태입니다. 파킨슨병 등 도파민 관련 연구용으로 적합합니다.
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Applications
- Western Blot (WB): 1–5 µg/mL
- ELISA: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D9 |
| Immunogen | NR4A2 (NP_006177, 147–250 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GSLHNFHQNY VATTHMIEQR KTPVSRLSLF SFKQSPPGTP VSSCQMRFDG PLHVPMNPEP AGSHHVVDGQ TFAVPNPIRK PASMGFPGLQ IGHASQLLDT QVPS*
Target Information
The Nuclear receptor related 1 protein (Nurr1), also known as NR4A2 (nuclear receptor subfamily 4, group A, member 2), is encoded by the NR4A2 gene in humans.
NURR1 is a member of the nuclear receptor family of intracellular transcription factors and plays a key role in maintaining the dopaminergic system of the brain.
Mutations in this gene are associated with disorders such as Parkinson’s disease, schizophrenia, and manic depression, and misregulation may be linked to rheumatoid arthritis.
Four transcript variants encoding distinct isoforms have been identified, with possible additional splice variants of undetermined full length.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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