Thermo Fisher Scientific HGK Monoclonal Antibody (3C7B5)
Human MAP4K4(HGK) 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 ELISA에 적합. 비결합형 액상 형태이며, 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3C7B5 |
| Immunogen | Purified recombinant fragment of MAP4K4 (aa400–500) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10986466 |
Product Specific Information
MA5-15423 targets MAP4K4 in indirect ELISA and WB applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of MAP4K4 (aa400–500) expressed in E. coli.
Target Information
MAP4K4 (HGK) is a serine/threonine kinase involved in stress-activated MAPK signaling pathways and cellular responses to environmental stress and cytokines such as TNF-alpha.
It acts upstream of the JUN N-terminal pathway and interacts with SH3 domain-containing adapter proteins like Nck.
HGK binds via its CNH regulatory domain to the N-terminal region of SPG3A.
Expression is ubiquitous across tissues; isoform 5 is more abundant in the brain, while isoform 4 predominates in liver, skeletal muscle, and placenta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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