Thermo Fisher Scientific HGK Monoclonal Antibody (3C7B5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

3C7B5

Immunogen

Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HGK,uniProtId:O95819-1,ncbiNodeId:9606,antigenRange:400-500,antigenLength:1239,antigenImageFileName:MA5-15423_HGK_O95819-1_House_mouse.svg,antigenImageFileNamePDP:MA5-15423_HGK_O95819-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.03% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_10986466

Product Specific Information

MA5-15423 targets MAP4K4 in indirect ELISA, WB applications and shows reactivity with Human samples.

The MA5-15423 immunogen is purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli.

Target Information

MAP4K4 (HGK) is a serine/threonine kinase which plays an important role in stress-activated MAPK core signaling pathways, the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.