Thermo Fisher Scientific Sodium Potassium ATPase alpha-1 Monoclonal Antibody (464.6)
Sodium Potassium ATPase α-1 단백질을 검출하기 위한 mouse monoclonal 항체. Western blot, IHC, ICC/IF, IP에 적합하며 인간 및 마우스 시료에 반응. 고순도 정제 항체로 PBS buffer에 보관, 4°C에서 안정적 저장 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Immunoprecipitation (IP) | 6 µL/mg of lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 464.6 |
| Immunogen | Full length native protein, purified |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 6.8–7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunocytochemistry: Epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE cell sections.
Target Information
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, specifically the Na⁺/K⁺-ATPases subfamily. Na⁺/K⁺-ATPase is an integral membrane protein responsible for maintaining the electrochemical gradients of Na⁺ and K⁺ ions across the plasma membrane. These gradients are essential for osmoregulation, sodium-coupled transport, and electrical excitability of nerve and muscle cells.
This enzyme consists of two subunits: a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The alpha subunit of Na⁺/K⁺-ATPase is encoded by multiple genes, and this antibody targets the alpha-1 subunit. Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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