Thermo Fisher Scientific BMP-10 Polyclonal Antibody
BMP-10 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot에 최적화되어 있으며, 인간과 랫트 반응성을 가짐. 항원 친화 크로마토그래피로 정제된 액상 형태로, 연구용으로 심근세포 증식 관련 BMP 신호 경로 연구에 적합.
- 판매단위
- pk
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Thermo Fisher Scientific BMP-10 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:2,000
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human BMP10 (aa 100–310/424) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913509 |
Product Specific Information
- Positive Control: MCF-7 cell lysate, 293 cell lysate, rat liver tissue lysate
- Subcellular Location: Secreted
Target Information
Bone morphogenetic proteins (BMPs) are a subfamily within the TGF-beta superfamily of signaling proteins. BMP-10 plays a crucial role in embryonic heart development by stimulating and maintaining cardiomyocyte proliferation. It signals through receptor complexes including BMPR-1A, BMPR-1B, ALK1, ALK3, and ALK6, inducing SMAD-dependent and SMAD-independent pathways. BMP-10 is structurally related to BMP-9, and both can inhibit endothelial cell proliferation and migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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