Thermo Fisher Scientific Myc Tag Monoclonal Antibody (Myc.A7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

View 32 publications 32 publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:500-1:2,000

View 8 publications 8 publications

ELISA (ELISA)

Assay-dependent

View 1 publication 1 publication

Immunoprecipitation (IP)

5 µg

View 9 publications 9 publications

ChIP assay (ChIP)

2.5 µg/10^6 cells

-

Product Specifications

Species Reactivity

Tag

Published species

Tag

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

Myc.A7

Immunogen

Synthetic peptide: EQKLISEEDL (Myc).

Conjugate

Unconjugated Unconjugated Unconjugated

View additional formats

• Biotin
• DyLight 488
• DyLight 550
• DyLight 650
• DyLight 680
• DyLight 800 4X PEG
• HRP
• Request custom conjugation

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_558473

Product Specific Information

MA1-21316 detects N-terminal or C-terminal Myc tagged fusion proteins.

MA1-21316 may be stored at 4° C short term. Add 0.05% sodium azide if desired. For long term storage, store at -20° C, avoiding freeze/thaw cycles.

Target Information

Myc is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.