Thermo Fisher Scientific TNFRSF11B Polyclonal Antibody, MaxPab
TNFRSF11B 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응합니다. Western blot에 적합하며, Affinity chromatography로 정제된 액상 형태입니다. PBS(pH 7.4) 버퍼에 보존되며 방부제 무첨가, -20°C에서 보관합니다.
- 카탈로그번호
- H00004982-D01P
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | TNFRSF11B (AAH30155.1, 1–401 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MNNLLCCALV FLDISIKWTT QETFPPKYLH YDEETSHQLL CDKCPPGTYL KQHCTAKWKT VCAPCPDHYY TDSWHTSDEC LYCSPVCKEL QYVKQECNRT HNRVCECKEG RYLEIEFCLK HRSCPPGFGV VQAGTPERNT VCKRCPDGFF SNETSSKAPC RKHTNCSVFG LLLTQKGNAT HDNICSGNSE STQKCGIDVT LCEEAFFRFA VPTKFTPNWL SVLVDNLPGT KVNAESVERI KRQHSSQEQT FQLLKLWKHQ NKDQDIVKKI IQDIDLCENS VQRHIGHANL TFEQLRSLME SLPGKKVGAE DIEKTIKACK PSDQILKLLS LWRIKNGDQD TLKGLMHALK HSKTYHFPKT VTQSLKKTIR FLHSFTMYKL YQKLFLEMIG NQVQSVKISC L
Target Information
The protein encoded by this gene is a member of the TNF-receptor superfamily.
This protein acts as an osteoblast-secreted decoy receptor and functions as a negative regulator of bone resorption. It specifically binds to osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart suggest roles in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants have been reported, though their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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