Thermo Fisher Scientific TG Monoclonal Antibody (OTI8F1), TrueMAB
인간 Thyroglobulin을 인식하는 Mouse IgG1 단클론 항체로, IHC(P)에서 1:150 희석 비율로 검증됨. 무보존 Lyophilized 형태이며, PBS/trehalose 버퍼에 저장. 연구용으로만 사용 가능하며, 갑상선 질환 및 암 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8F1 |
| Immunogen | Human recombinant protein fragment (aa 20–358 of human TG) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones (T4 and T3).
Anti-thyroglobulin autoantibodies are associated with autoimmune thyroid diseases such as Hashimoto thyroiditis and Graves disease, with elevated levels in Hashimoto thyroiditis.
Anti-hTG is also characteristic of thyroid cancer and can be used for patient follow-up.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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