Thermo Fisher Scientific ANKMY2 Monoclonal Antibody (OTI1C12)
ANKMY2 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot과 IHC(P)에서 검증됨. Human 시료에 반응하며, Mouse IgG1 아이소타입. 액상 형태로 제공되며, -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:400–1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C12 |
| Immunogen | Full length human recombinant protein of ANKMY2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723875 |
Target Information
ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein containing three ANK repeats and one MYND-type zinc finger.
It is encoded by a gene located on human chromosome 7p21.1 and is conserved across multiple species including chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito, and C. elegans.
Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, suggests a potential role in the pathogenesis of NK-cell malignancies.
ANKMY2 is also upregulated by enforced expression of Hox11, which affects hematopoiesis and may promote pre-leukemic states.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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