Thermo Fisher Scientific DOCK8 Monoclonal Antibody (OTI12D7), TrueMAB
DOCK8 단백질을 인식하는 단일클론 항체로 인간 시료에 반응. Western blot 및 IHC(P) 응용에 적합. 동결건조 형태로 제공되며, 보존제가 없는 PBS 버퍼에 저장. 면역 반응 연구 및 단백질 발현 분석에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12D7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 84–405 of human DOCK8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
The Dedicator of cytokinesis protein 8 (DOCK8) belongs to the DOCK180 family of guanine nucleotide exchange factors.
DOCK8 plays a crucial role in humoral immune responses and in the formation of the B cell immunological synapse.
Mutations in the DOCK8 gene cause the autosomal recessive form of hyper-IgE syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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